Hill plays a man diagnosed with schizophrenia, while Stone plays a woman fixated on broken relationships. Both sign up to test a mysterious pill believed to cure anything about the mind, but things do not go as planned.
Cindy Holland, vice president of Netflix original series, announced its debut date, Sept. 21, during a panel at the Television Critics Association's summer meeting. Holland called "Maniac" a "thought-provoking, fever dream of a show."
The actors starred opposite each other in the 2007 teen comedy "Superbad."