They last met when Tsitsipas beat Cuevas 6-3, 7-6 (4) in Estoril in May 2019 for his only tour-level title to date on clay. The Greek player, ranked sixth in the world, is building momentum on clay after losing in the first round in Rome last week.
His quarterfinal opponent is Dusan Lajovic, who swept past eighth-seeded Karen Khachanov 6-1, 6-2 in their second-round match. Since the tour restarted amid the coronavirus pandemic, Khachanov has gone four tournaments without making the quarterfinals.
After knocking out top-seeded Daniil Medvedev in the first round, France's Ugo Humbert followed it up with a 6-4, 6-3 win over Jiri Vesely to reach his first career ATP quarterfinal on clay. He will face Casper Ruud after the Norwegian won 6-3, 6-3 against the sixth-seeded Fabio Fognini, who was champion in Hamburg in 2013.
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