“An HIV vaccine is essential to end the global pandemic and we hoped this vaccine candidate would work. Regrettably, it does not,” said NIH infectious diseases chief Dr. Anthony Fauci. There were no safety concerns, but NIH, which sponsored the study, agreed that vaccinations should stop.
The experimental shot was based on the only vaccine ever shown to offer even modest protection against HIV, one that was deemed 31% effective in Thailand. That wasn’t good enough for real-world use but gave scientists a starting point. They beefed up the shot and adapted it to the HIV subtype that’s common in southern Africa.
Two other large studies, in several countries, are under way testing a different approach to a possible HIV vaccine.
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