The suspensions were announced Saturday by the commissioner's office. Both are 40-man roster players. These are the fourth suspensions this year under the major league drug program. Also banned were Pittsburgh All-Star outfielder Starling Marte and Philadelphia pitcher Elniery Garcia. There have been 47 suspensions this year under the minor league program.
Colon is a 27-year-old right-hander who made his big league debut with the Indians last July 8 and was 1-3 with a 7.20 ERA in 11 relief appearances. He has a 4.13 ERA in 28 relief appearances this year at Triple-A Columbus.
The 25-year-old Gregorio is 4-4 with a 3.04 ERA in 13 starts this year at Triple-A Sacramento.